Publications

Comparable reliability and acceptability of telepsychiatry and face-to-face psychiatric assessments in the emergency room setting
 

Moises BistreAlzbeta Juven-WetzlerDaniel ArgoIgor BarashGregory KatzRonen Teplitza, Muhamad-Musa SaidYoav KohnOmer Linkovski & Renana Eitan

Published: 26 Sep 2021

This study aims to compare the reliability and acceptability of psychiatric interviews using telepsychiatry and face-to-face modalities in the emergency room setting.

Increased activation product of complement 4 protein in plasma of individuals with schizophrenia
 


Published: 22 September 2021

Structural variation in the complement 4 gene (C4) confers genetic risk for schizophrenia. The variation includes numbers of the increased C4A copy number, which predicts increased C4A mRNA expression. C4-anaphylatoxin (C4-ana) is a C4 protein fragment released upon C4 protein activation that has the potential 

A school-based health and mindfulness curriculum improves children’s objectively measured sleep: a prospective observational cohort study

Published: july 6, 2021

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

Examining subjective sleep quality in adults with hoarding disorder

Mahnke, A.*, Linkovski, O.*, Timpano, K., Sanchez, C., Varias, A., Filippou-Frye, M., Blasey, C., Bernert, R., & Rodriguez, C. I.
Published: Journal of Psychiatric Research, 2021.

Hoarding disorder (HD), characterized by difficulty parting with possessions and functionally impairing clutter, affects 2–6% of the population. Originally considered part of Obsessive-Compulsive Disorder (OCD), HD became a distinct diagnostic entity in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) in 2013. While sleep impacts OCD, little is known about sleep in HD. As HD patients often report poor sleep

Comparable Validity of Telepsychiatry and Face-to- Face Psychiatric Assessment in Emergency Room Setting

Bistre, M., Wetzler, A. J., Argo, D., Barash, I., Katz, G., Teplitz, R., Said, M. M., Kohn Y.,Linkovski, O.* & Eitan, R.
Published: International Journal of Psychiatry in Clinical Practice, 2021.

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

In vivo complement activation product, C4, elevated in plasma from patients with schizophrenia compared to healthy controls in pilot study

Kalinowski, A., Liliental, J., Anker, L., Linkovski, O., Culbertson, C., Hall, J., Pattni, R.,O’Hara, R., Hallmayer, J., Ballon, J., & Urban, A.
Published: Translational Psychiatry, 2021

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

High-Resolution spectral sleep analysis reveals a novel association between slow oscillations and memory retention in elderly adults

Kawai, M., Schneider, L., Linkovski, O., Jordan, T. J, Karna R. S., Pirog, S., Cotto, I., O’hara, R.
Published: Frontiers in Aging Neuroscience, 2021
 

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

Why Check? A meta-analysis of checking in Obsessive-Compulsive Disorder: Threat vs. Distrust of Senses

Strauss, Y. A., Fradkin, I., McNally, J. R., Linkovski, O., Anholt, G., Huppert D. J.
Published: Clinical Psychology Review, 2020

Compulsive checking is the most common ritual among individuals with obsessive-compulsive disorder (OCD). Yet, other than uncertainty, the variables prompting checking are not fully understood. Laboratory studies suggest that task conditions - whether threatening (anxiety-relevant) or neutral, and task type - whether requiring perceptual or reasoning decision-making – may be influential. The purpose of our...

Critical time intervention for individuals with hoarding disorder at risk for eviction

Millen, A.*, Levinson, A.*, Linkovski, O., Shuer, L., Feldman, T., Gilbert, N. A., Johns,G. K., Vargas, S. M., Rottier, K. A., Joyner, E., Girson, R. B., Zwerling, J., Sonnenfeld,D., Shapiro, A. M., Tannen, A., Conover, S. Dixon, L., Essock, S., Herman, D., Simpson,H. B., & Rodriguez, C. I.
Published: Psychiatric Services, 2020
 

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

Exploring BDNF Val66Met polymorphism and ketamine response in Obsessive-Compulsive Disorder: A preliminary study

Linkovski, O., Wheaton, M. G., Zwerling, J., Odgerel, Z., van Roessel, P., Filippou-Frye, M., Lombardi, A., Wright, B., Steinman, S. A., Simpson, H. B., Lee, F., & Rodriguez. C. I.
Published: Journal of Clinical Psychopharmacology, 2019

Acommon single-nucleotide polymorphism (SNP) in the human brain derived neurotrophic factor (BDNF) gene (Val66Met; rs6265) has been reported to alter extinction learning in human carriers and knock-in mice with the SNP. Extinction learning is a major component of behavioral therapies for anxiety disorders...

Beyond uncertainty: a broader scope for incentive hope mechanisms and its implications

Linkovski, O., Weinbach, N., Edelman, S., Feldman M. W., Lotem, A., & Kolodny, O.
Published: Behavioral and Brain Sciences, 2019

We propose that food-related uncertainty is but one of multiple cues that predicts harsh conditions and may activate “incentive hope.” An evolutionarily adaptive response to these would have been to shift to a behavioral-metabolic phenotype geared toward facing hardship. In modernity, this phenotype may lead to pathologies such as obesity and hoarding. Our perspective suggests a novel therapeutic approach...

The Future of Dementia Biomarkers Needs Better Neuropsychology

Naparstek, S.*, Linkovski, O.*, & O’Hara, R. 
Published: American Journal of Psychiatry, 2019

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

Effects of rapastinel (formerly GLYX-13) on Serum brain derived neurotropic factor (BDNF)

Linkovski, O., Shen, H., Zwerling, J., Filippou-Frye, M., Jo, B., Cordell, E., Cooper, T. B., Simpson, H. B., Burch, R. M., Moskal, J. R., Lee, F., & Rodriguez. C. I.
Published: Journal of Clinical Psychiatry, 2018

Sound ethical decision making is essential to astute and compassionate clinical care. Wise practitioners readily identify and reflect on the ethical aspects of their work. They engage, often intuitively and without much fuss, in careful habits—in maintaining therapeutic boundaries; in consulting with experts when caring..

Augmenting buried in treasures with in-home uncluttering practice: pilot study in hoarding disorder

Linkovski, O., Zwerling, J., Cordell, E., Sonnenfeld, D., Willis, H., La Lima, N. C., Baker., C., Ghazzaouli, R., Sanchez, C., Wright, B., Alford., M., Varias, A., Filippou-Frye, M., Shuer, L., Frost, R., & Rodriguez, C. I.
Published: Journal of Psychiatric Research, 2018

Hoarding disorder is characterized by difficulty parting with possessions and by clutter that impairs the functionality of living spaces. Cognitive behavioral therapy conducted by a therapist (individual or in a group) for hoarding symptoms has shown promise. For those who cannot afford or access the services of a

Mirror neurons in mirror-touch synesthesia

Linkovski, O., Katzin, N., Salti, M.
Published: The Neuroscientist, 2017

More than 20 years ago, a seminal article from Rizzolatti’s laboratory (di Pellegrino and others 1992) revealed a population of neurons in monkeys’ premotor regions that exhibited a similar pattern of activity when monkeys viewed an action and when they conducted the action. Rizzolatti named these neurons “mirror...

Training and transfer in aging – Is pathways overlap really necessary

Aisenberg, D., Cohen, Z., & Linkovski, O.
Published: Cognitive Neuroscience, 2017

The literature on aging shows clear effects of changes in white matter on cognitive performance, but these changes cannot solely account for behavioral differences seen in reaction-time tasks(Kennedy & Raz, 2009). The transfer effect of training in aging has been widely reviewed Many studies showed transfer effects to...

Ethical Challenges in Treating Hoarding Disorder: Two primary care clinical case studies

Millen, A., Linkovski, O., Dunn, L., & Rodriguez, C. I.
Published: FOCUS: The Journal of Lifelong Learning in Psychiatry,2017

Sound ethical decision making is essential to astute and compassionate clinical care. Wise practitioners readily identify and reflect on the ethical aspects of their work. They engage, often intuitively and without much fuss, in careful habits—in maintaining therapeutic boundaries; in consulting with experts when caring..

Inhibiting uncertainty: priming inhibition promotes reduction of uncertainty

Kalanthroff, E.,* Linkovski, O.,* Anholt, G., & Henik, A.
Published: Neuropsychologia, 2016

Uncertainty affects performance in many cognitive tasks, including the visual-search task, and individual differences in the experience of uncertainty may contribute to several psychological disorders. Despite the importance of uncertainty, to date, no study has explained the basic mechanisms underlying individual differences in the experience of uncertainty. However, it has been suggested that inhibition, a cognitive... 

Stop checking: Repeated checking and its effects on response inhibition and doubt

Linkovski, O., Kalanthroff, E., Anholt, G., & Henik, A.
Published: Journal of Behavior Therapy and Experimental Psychiatry, 2016

Repeated checking is a common ritual in obsessive-compulsive disorder (OCD). van den Hout and Kindt (2003b) devised a task demonstrating paradoxical reductions in memory confidence following repeated checking. This effect was later found to be contingent upon response inhibition. The current study aims to...

Inhibitory deficits in obsessive-compulsive patients: Heterogeneity in medicated patients

Kalanthroff, E., Teichert, T., Wheaton, M., Ahmari, S., Kimeldorf, M., Linkovski, O.,
Fyer, A., Schneier, F., Anholt, G., & Simpson, H. B.

Published: Depression and Anxiety, 2016

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in 

What underlies the effect of sleep disruption? The role of alertness in obsessive- compulsive disorder (OCD)

Kalanthroff, E., Linkovski, O., Weinbach, N., Anholt, G., & Simpson, H. B.
Published: Journal of Behavior Therapy and Experimental Psychiatry, 2016

Several recent investigations report a correlation between shorter sleep duration and obsessive-compulsive disorder (OCD) symptoms. In a recent study, Nota, Schubert, and Coles (2016) investigated the potential underlying mechanism of this correlation and found that shorter sleep duration was associated with worse...

Musical space synesthesia: Automatic, explicit and conceptual connections between musical stimuli and space

Akiva-Kabiri, L.,* Linkovski, O.,* Gertner, L., & Henik, A.
Published: Consciousness and Cognition, 2014

In musical–space synesthesia, musical pitches are perceived as having a spatially defined array. Previous studies showed that symbolic inducers (e.g., numbers, months) can modulate response according to the inducer’s relative position on the synesthetic spatial form. In the current study we tested two musical–space..

Did I turn off the stove? Good inhibitory control can protect from influences of repeated checking

Linkovski, O.,* Kalanthroff, E.,* Anholt, G., & Henik, A.
Published: Journal of Behavior Therapy and Experimental Psychiatry, 2013

Obsessive-compulsive disorder (OCD) is an anxiety disorder characterized by compulsions aimed at reducing anxiety associated with intrusive cognitions. However, compulsive behaviors such as repeated checking were found to increase rather than decrease uncertainty related to obsessive thoughts...

Is it for real? Evaluating authenticity of musical pitch-space synesthesia

Linkovski, O., Akiva-Kabiri, L., Gertner, L., & Henik, A.
Published: Cognitive Processing, 2012

In spatial-sequence synesthesia, ordinal sequences are visualized in explicit spatial locations. We examined a recently documented subtype in which musical notes are represented in spatial configurations, to verify consistency and automaticity of musical pitch-space (M-S) synesthesia. An M-S synesthete performed...

If I do it, it must be important: Integrating basic cognitive research findings with cognitive behavior theory

Anholt, G., Linkovski, O., Kalanthroff, E., Henik, A.
Published: Psicoterapia Cognitiva e Comportamentale, 2012

Poor sleep impedes children’s cognitive, emotional, and psychosocial development. Pediatric sleep dysregulation is common, and children who live in communities of low socioeconomic status (SES) experience additional risk factors for short sleep duration and poor sleep quality. School-based training in